Benzylpenicillin
Benzylpenicillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
102 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syphilis | D013587 | EFO_0007504 | A53.9 | 1 | 4 | 6 | 7 | 3 | 20 |
| Infections | D007239 | EFO_0000544 | — | — | 2 | 5 | 7 | 2 | 15 |
| Communicable diseases | D003141 | — | — | — | — | 2 | 5 | 2 | 9 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | 1 | 4 | 1 | 2 | 7 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | — | 2 | 2 | 2 | 6 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | 2 | 1 | 1 | 4 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | 1 | — | 3 | — | 4 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | 1 | — | 1 | 2 | 4 |
| Yaws | D015001 | EFO_0007548 | A66 | — | — | 2 | 1 | — | 3 |
| Respiratory tract infections | D012141 | — | J06.9 | — | — | — | 1 | 2 | 3 |
Show 22 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bacterial infections | D001424 | — | A49 | — | — | 1 | — | 2 | 3 |
| Neurosyphilis | D009494 | EFO_0007339 | A50.40 | — | — | 1 | — | 2 | 3 |
| Treponemal infections | D014211 | EFO_1001217 | — | — | — | 2 | — | — | 2 |
| Neonatal sepsis | D000071074 | — | — | — | — | 1 | — | 1 | 2 |
| Toxemia | D014115 | — | — | — | — | 1 | — | 1 | 2 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 1 | 1 | — | — | 1 |
| Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | — | 1 | 1 | — | — | 1 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | 1 | — | — | 1 |
| Microbial drug resistance | D004352 | — | — | — | — | 1 | — | — | 1 |
| Severe acute malnutrition | D000067011 | — | — | — | — | 1 | — | — | 1 |
Show 17 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 2 | — | — | 2 | 4 |
| Rheumatic heart disease | D012214 | EFO_1001161 | I09.9 | — | 2 | — | — | 2 | 4 |
| Rheumatic diseases | D012216 | — | M79.0 | — | 2 | — | — | 1 | 3 |
| Urinary bladder neoplasms | D001749 | — | C67 | 2 | 1 | — | — | — | 3 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 2 | 1 | — | — | — | 3 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 1 | — | — | 1 | 2 |
| Congenital syphilis | D013590 | EFO_0007219 | A50 | — | 1 | — | — | 1 | 2 |
| Covid-19 | D000086382 | — | U07.1 | — | 1 | — | — | — | 1 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | 1 | — | — | — | 1 |
| Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | — | 1 | — | — | — | 1 |
Show 4 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Streptococcal infections | D013290 | EFO_1001476 | — | 1 | — | — | — | 1 | 2 |
| Pharyngitis | D010612 | — | R07.0 | 1 | — | — | — | 1 | 2 |
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
| Atrophy | D001284 | — | — | 1 | — | — | — | — | 1 |
| Bone regeneration | D001861 | — | — | 1 | — | — | — | — | 1 |
| Bacterial vaginosis | D016585 | EFO_0003932 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Impacted tooth | D014095 | — | K01.1 | — | — | — | — | 2 | 2 |
| Drug monitoring | D016903 | — | — | — | — | — | — | 1 | 1 |
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
| Critical illness | D016638 | — | — | — | — | — | — | 1 | 1 |
| Hiv seropositivity | D006679 | — | — | — | — | — | — | 1 | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Urinary incontinence | D014549 | — | R32 | — | — | — | — | 1 | 1 |
| Stress urinary incontinence | D014550 | — | — | — | — | — | — | 1 | 1 |
| Enuresis | D004775 | — | R32 | — | — | — | — | 1 | 1 |
| Hepatitis c | D006526 | — | B19.2 | — | — | — | — | 1 | 1 |
Show 21 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzylpenicillin |
| INN | benzylpenicillin |
| Description | Benzylpenicillin is a penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. It has a role as an antibacterial drug, an epitope and a drug allergen. It is a penicillin allergen and a penicillin. It is a conjugate acid of a benzylpenicillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 61-33-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL29 |
| ChEBI ID | 18208 |
| PubChem CID | 5904 |
| DrugBank | DB01053 |
| UNII ID | Q42T66VG0C (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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5,832 adverse events reported
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