Benzylpenicillin
Benzylpenicillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
912 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 12 | 24 | 57 | 126 | 70 | 274 |
| Communicable diseases | D003141 | — | — | 1 | 6 | 27 | 43 | 27 | 101 |
| Helicobacter infections | D016481 | EFO_1000961 | — | 4 | 8 | 20 | 39 | 25 | 92 |
| Pneumonia | D011014 | EFO_0003106 | J18 | 6 | 11 | 23 | 19 | 20 | 71 |
| Gastritis | D005756 | EFO_0000217 | K29.7 | 3 | 2 | 7 | 18 | 4 | 33 |
| Healthy volunteers/patients | — | — | — | 20 | — | 1 | 3 | 7 | 31 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | 2 | 3 | 7 | 11 | 10 | 31 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | 5 | 6 | 10 | 7 | 26 |
| Bacterial infections | D001424 | — | A49 | 4 | 3 | 2 | 9 | 6 | 24 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | 1 | 5 | 12 | 6 | 24 |
Show 178 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | — | 5 | 6 | — | 4 | 13 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 1 | 6 | 2 | — | 1 | 9 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 2 | 3 | — | 4 | 7 |
| Abscess | D000038 | EFO_0003030 | — | — | 1 | 3 | — | 2 | 6 |
| Treponemal infections | D014211 | EFO_1001217 | — | — | 1 | 4 | — | — | 5 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | 2 | 4 | — | — | 5 |
| Leukemia | D007938 | — | C95 | — | 2 | 3 | — | 2 | 5 |
| Hematologic neoplasms | D019337 | — | — | — | 2 | 2 | — | 2 | 5 |
| Multiple myeloma | D009101 | — | C90.0 | — | 2 | 3 | — | 2 | 5 |
| Rheumatic heart disease | D012214 | EFO_1001161 | I09.9 | — | 2 | 1 | — | 2 | 5 |
Show 87 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | 1 | — | — | 3 | 4 |
| Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | — | 4 | — | — | — | 4 |
| B-cell lymphoma marginal zone | D018442 | — | C88.4 | — | 1 | — | — | 2 | 3 |
| Gastrointestinal microbiome | D000069196 | — | — | — | 1 | — | — | 1 | 2 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | — | 1 | — | — | 1 | 2 |
| Systemic inflammatory response syndrome | D018746 | EFO_1001478 | R65.10 | — | 1 | — | — | 1 | 2 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 1 | — | — | 1 | 2 |
| Cleft palate | D002972 | EFO_0003920 | Q35 | — | 1 | — | — | 1 | 2 |
| B-cell lymphoma | D016393 | — | — | — | 1 | — | — | 1 | 2 |
| Tonsillectomy | D014068 | — | — | 1 | 1 | — | — | 1 | 2 |
Show 29 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Impacted tooth | D014095 | — | K01.1 | 1 | — | — | — | 4 | 5 |
| Pharmacokinetics | D010599 | — | — | 2 | — | — | — | 2 | 4 |
| Drug interactions | D004347 | — | — | 3 | — | — | — | — | 3 |
| Gastrointestinal diseases | D005767 | — | — | 1 | — | — | — | 2 | 3 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | 1 | — | — | — | 2 | 3 |
| Chemical and drug induced liver injury | D056486 | EFO_0004228 | — | 1 | — | — | — | 1 | 2 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | 1 | — | — | — | 1 | 2 |
| Respiration disorders | D012120 | — | J00-J99 | 2 | — | — | — | — | 2 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 2 | — | — | — | — | 2 |
| Jaw fractures | D007572 | — | — | 1 | — | — | — | — | 1 |
Show 16 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kwashiorkor | D007732 | EFO_1001009 | E40 | — | — | — | — | 4 | 4 |
| Hematopoietic stem cell transplantation | D018380 | — | — | — | — | — | — | 2 | 2 |
| Seizures | D012640 | — | G40.4 | — | — | — | — | 2 | 2 |
| Gram-positive bacterial infections | D016908 | — | — | — | — | — | — | 2 | 2 |
| Protein-energy malnutrition | D011502 | EFO_0009563 | E41 | — | — | — | — | 2 | 2 |
| Thyroid nodule | D016606 | EFO_1001436 | — | — | — | — | — | 2 | 2 |
| Periapical periodontitis | D010485 | EFO_1001391 | K04.5 | — | — | — | — | 2 | 2 |
| Gingival recession | D005889 | — | K06.0 | — | — | — | — | 2 | 2 |
| Cachexia | D002100 | — | R64 | — | — | — | — | 2 | 2 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
Show 116 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzylpenicillin |
| INN | benzylpenicillin |
| Description | Benzylpenicillin is a penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. It has a role as an antibacterial drug, an epitope and a drug allergen. It is a penicillin allergen and a penicillin. It is a conjugate acid of a benzylpenicillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 61-33-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL29 |
| ChEBI ID | 18208 |
| PubChem CID | 5904 |
| DrugBank | DB01053 |
| UNII ID | Q42T66VG0C (ChemIDplus, GSRS) |
Target
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Safety
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Adverse Events
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7,256 adverse events reported
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