Benzylpenicillin
Benzylpenicillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Penicillin g, Penicillin g potassium, Pfizerpen (discontinued: Penicillin, Penicillin g, Penicillin g potassium, Pentids, Pfizerpen, Pfizerpen g)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bicillin c-r 900/300 | New Drug Application | 2024-06-03 |
| bicillin cr | New Drug Application | 2024-06-04 |
| bicillin l-a | New Drug Application | 2024-07-12 |
| buffered penicillin g potassium | ANDA | 2025-01-08 |
| extencilline | unapproved drug for use in drug shortage | 2024-07-18 |
| lentocilin | unapproved drug for use in drug shortage | 2024-06-07 |
| penicillin g potassium | ANDA | 2025-04-30 |
| penicillin g sodium | ANDA | 2020-05-27 |
| pfizerpen | ANDA | 2024-12-12 |
Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CE: Beta-lactamase sensitive penicillins
— J01CE01: Benzylpenicillin
— J01CE08: Benzathine benzylpenicillin
— J01CE09: Procaine benzylpenicillin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA14: Benzylpenicillin
HCPCS
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Clinical
Clinical Trials
102 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzylpenicillin |
| INN | benzylpenicillin |
| Description | Benzylpenicillin is a penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. It has a role as an antibacterial drug, an epitope and a drug allergen. It is a penicillin allergen and a penicillin. It is a conjugate acid of a benzylpenicillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 61-33-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL29 |
| ChEBI ID | 18208 |
| PubChem CID | 5904 |
| DrugBank | DB01053 |
| UNII ID | Q42T66VG0C (ChemIDplus, GSRS) |
Target
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Variants
No data
Financial
No data
Trends
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Safety
Black-box Warning
Black-box warning for: Bicillin c-r 900/300, Bicillin cr, Bicillin l-a
Adverse Events
Top Adverse Reactions
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5,725 adverse events reported
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